sparsentan will reduce the extent or result of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and lessens efficacy associated with these substrates.fosphenytoin will reduce the level or outcome of modafinil by affecting hepatic/intestinal

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